Pharmaceutical-based Cancer Treatment

Chemistry

Pharmaceutical-based Cancer Treatment

Cancer treatment is extremely costly, frequently physically taxing and never guaranteed to work. However, as drug companies strive to improve conditions with regard to the latter two characteristics, we must face a worsening set of conditions with respect to the first characteristic. The focus of the present research proposal is on using newly focused ways of fighting cancer cells without attacking their healthy host cells, particularly with an emphasis on the genetic characteristics of breast cancer treatment. We proceed with the hypothesis that there is great opportunity for the improvement of treatment outcomes and financial growth potential for the drug company which successfully develops a breast-cancer cell-specific drug therapy.

As the research endeavor would demonstrate, there is today an ongoing discussion on addressing cancer through more refined and targeted approaches that has ultimately lead to the decision to explore genomic opportunities to address breast cancer. According to Singer (2011), “the growing understanding of cancer genetics has enabled researchers to develop an increasing number of drugs designed to zero in on cancer cells. Varma says Blueprint will use genomics and novel chemistry to develop such drugs in a more systematic way, targeting a broader range of molecular mistakes.” (Singer, p. 1)

Today, there is an increasingly imperative to develop the kinds of cancer treatment drugs which either supplant or at least supplement the use of more aggressive radiation treatment strategies. According to the Economist (2011), the FDA has accelerated the pace by which cancer drug patents expire in order to make these costly treatment processes both more accessible and more affordable. As a result, the Economist reports, many drug companies have turned their attention to the development of more targeted and specific treatments for various types of cancer. This denotes a topic that is ripe for research and rife with opportunities for new discovery.

Topic 2: Corn Ethanol as an Alternative Fuel Source

The world’s consumption of fossil fuels is leading us collectively to a point of critical mass. The combination of its negative impact on the natural environment and its finite availability have led us to collectively investigate a number of ways in which alternative fuel sources might be produced and distributed in its place. The emphasis on petroleum in supporting our way of life and the need to supplant this with a more sustainable, clean-burning and more accessible fuel source mutually drive the research proposal here. This asserts that though there is a need, beyond any reasonable doubt, for us to produce an efficient and sustainable alternative fuel method. However, the focus in this discussion on the alternative source known as corn ethanol will also direct the attention of the proposed study toward those proposed alternative fuel sources that are otherwise problematic and highly imperfect.

Many of its advocates have proposed corn ethanol as a fuel source capable of running an automobile engine or a warehouse of machinery. Indeed, according to Holt-Gimenex, “biofuel champions assure us that because fuel crops are renewable, they are environment-friendly, can reduce global warming and will foster rural development. But the tremendous market power of biofuel corporations, coupled with the poor political will of governments to regulate their activities, make this unlikely.” (Holt-Gimenez, 2)

These ulterior motives of the above-mentioned biofuel companies will enter into the discussion as the research process advances and will be illuminated with the interest of scrutinizing ethanol for the inefficiency of its production process. The study would set out to prove that corn ethanol is a poor choice for the replacement of petroleum.

Topic 3: Discovering LSD

Few subjects invoke more controversy, emotion and distortion than that of illegal drugs. However, the class of psychedelic drugs that includes Lysergic acid dethylamide (LSD) has also had the effect of correlating to historically significant artistic, cultural and philosophical movements. As a result, the substance does invite some greater conceptual scrutiny than the simple legal prohibition which currently applies to it. The purpose of the research proposed here would be to engage this scrutiny and to produce a comprehensive discussion on the chemical makeup, effects and history of the powerful hallucinogen.

The history of LSD centers on Swizz chemist Albert Hofmann. While working at the pharmaceutical labs of Sandoz, which is today known as Novartis, Hofmann would inadvertently experience the effects of LSD, becoming the first man to experience a synthesized psychedelic reaction in a laboratory setting. On the instance at which he stumbled upon LSD by unintentionally experiencing its effects, he reports that “Time and again I hear or read that LSD was discovered by accident. This is only partly true. LSD came into being within a systematic research program, and the “accident” did not occur until much later: when LSD was already five years old, I happened to experience its unforeseeable effects in my own body – or rather, in my own mind.” (Hofmann, 36)

The research proposed here would further investigate the invents surrounding this discovery, the chemical implications of its impact on the human cerebral cortex and the connection between Hofmann’s intended pharmaceutical work and his eventual revelation.

Works Cited:

Economist. (2011). The Costly War on Cancer. Economist.com.

Goozner, M. (2012). New Cancer Drugs: Affordable by the 1%? The Fiscal Times.

Hofmann, a. (1979). LSD-My Problem Child. MAPS.

Holt-Gimenez, E. (2007). The biofuel myth. International Herald Tribune.

Singer, E. (2011). Developing Cancer Drugs Based on Genomics. Technology Review.


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